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1.
Comput Biol Med ; 155: 106659, 2023 03.
Article in English | MEDLINE | ID: covidwho-2228829

ABSTRACT

Automatic segmentation of the lung parenchyma from computed tomography (CT) images is helpful for the subsequent diagnosis and treatment of patients. In this paper, based on a deep learning algorithm, a lung dense attention network (LDANet) is proposed with two mechanisms: residual spatial attention (RSA) and gated channel attention (GCA). RSA is utilized to weight the spatial information of the lung parenchyma and suppress feature activation in irrelevant regions, while the weights of each channel are adaptively calibrated using GCA to implicitly predict potential key features. Then, a dual attention guidance module (DAGM) is designed to maximize the integration of the advantages of both mechanisms. In addition, LDANet introduces a lightweight dense block (LDB) that reuses feature information and a positioned transpose block (PTB) that realizes accurate positioning and gradually restores the image resolution until the predicted segmentation map is generated. Experiments are conducted on two public datasets, LIDC-IDRI and COVID-19 CT Segmentation, on which LDANet achieves Dice similarity coefficient values of 0.98430 and 0.98319, respectively, outperforming a state-of-the-art lung segmentation model. Additionally, the effectiveness of the main components of LDANet is demonstrated through ablation experiments.


Subject(s)
COVID-19 , Humans , Algorithms , Thorax , Tomography, X-Ray Computed , Lung , Image Processing, Computer-Assisted
2.
Comput Biol Med ; 149: 105981, 2022 10.
Article in English | MEDLINE | ID: covidwho-1996099

ABSTRACT

the automatic segmentation of lung infections in CT slices provides a rapid and effective strategy for diagnosing, treating, and assessing COVID-19 cases. However, the segmentation of the infected areas presents several difficulties, including high intraclass variability and interclass similarity among infected areas, as well as blurred edges and low contrast. Therefore, we propose HADCNet, a deep learning framework that segments lung infections based on a dual hybrid attention strategy. HADCNet uses an encoder hybrid attention module to integrate feature information at different scales across the peer hierarchy to refine the feature map. Furthermore, a decoder hybrid attention module uses an improved skip connection to embed the semantic information of higher-level features into lower-level features by integrating multi-scale contextual structures and assigning the spatial information of lower-level features to higher-level features, thereby capturing the contextual dependencies of lesion features across levels and refining the semantic structure, which reduces the semantic gap between feature maps at different levels and improves the model segmentation performance. We conducted fivefold cross-validations of our model on four publicly available datasets, with final mean Dice scores of 0.792, 0.796, 0.785, and 0.723. These results show that the proposed model outperforms popular state-of-the-art semantic segmentation methods and indicate its potential use in the diagnosis and treatment of COVID-19.


Subject(s)
COVID-19 , Deep Learning , Attention , COVID-19/diagnostic imaging , Humans , Image Processing, Computer-Assisted/methods
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